Abstract Background: The navigator nurses were established to aid children with cancer by utilizing their practical experience and abilities to deliver patient-centered care, addressing physical, social, and emotional needs. They oversee the entire treatment process, empowering children, offering information and support and bridging the gap between children and health care team. The aim of this study was to improve oncology nurses' navigation core competencies toward caring for children with cancer. Subjects and Method: Design: A quasi-experimental design was used. Subjects: All available children and nurses who are working at oncology units of Benha Specialized pediatric in Benha City. Tools: Tool (I): A structured interview sheet, Tool (II): Oncology nurses’ navigator core competency scale, Tool (III): Medical data of the studied pediatric oncology &Pediatric oncology patient's satisfaction. Results: It was found that the vast majority of the studied nurses had an incompetent level of navigation core competencies at the pre- navigation implementation which improved to majority of them had a competent level of navigation competency post- and follow-up navigation implementation. Conclusion: The present study findings showed that navigation program has positive effect on nurses' navigation core competencies toward caring for children with cancer. Recommendations: Refreshing courses pre-service and in- services navigation programs to enhance nurses' navigation core competencies level toward caring for children with cancer.
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