Abstract Background: Organizational cynicism is a critical cause for the nurses’ negative attitudes toward their healthcare organization. Organizational cynicism is harmful viewpoint that has an impact on nurses' trustfulness and work embeddedness. Aim: Investigate the effect of organizational cynicism behaviors on nursing staff work embeddedness. Subjects and Method: Design: A descriptive correlational study design was used to conduct this study. Setting: The study was conducted at all intensive care units and inpatient departments of Samannoud General Hospital. Subjects: This study included 530 nurses. Tools: Tool I: Organizational Cynicism Behaviors Scale. Tool II: Work Embeddedness Scale. Results: About half (50.4%) of the nursing staff had moderate level of organizational cynicism behaviors. 24.4% and 57.5% of nursing staff had high and moderate levels of cognitive cynicism. A high percentage (69.4%) of the nursing staff had a low level of work embeddedness. More than half (56.4%) of the nursing staff had a high level of nurse community links dimension. Conclusion: There was a statistically significant negative correlation between organizational cynicism behaviors and work embeddedness among nursing staff. Recommendations: Hospital’s administration should conduct constantly regular training programs for nursing staff in different healthcare units, to increase their awareness about organizational cynicism. Head nurses should allow staff nurses to participate in decision making processes, especially in issues related to them.