Document Type : Original Article
Authors
1
Assistant Professor of Adult Medical Surgical Nursing Department, Faculty of Nursing, South Valley University, Qena, Egypt
2
Assistant professor of clinical oncology, Faculty of Medicine, South Valley University, Qena, Egypt.
3
Assistant Professor of Nursing Administration Department, Faculty of Nursing, Irbid National University, Irbid, Jordan.
4
Assistant Professor of Critical Nursing Department, Faculty of Nursing, Irbid National University, Irbid, Jordan.
5
Assistant Professor of Surgical Oncology Department, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
6
Assistant professor of physical therapy department, faculty of Medical Applied, Irbid national University, Jordan.
Abstract
Background: Breast cancer is the most often diagnosed disease and the main cause of
death between females globally. Different chemotherapeutic are used, such as
doxorubicin or epirubicin in combination with cyclophosphamide, and paclitaxel
(Taxol) or docetaxel in combination with carboplatin Aims: the study aimed to
evaluate effect of implementing bundle of care on breast cancer patients paclitaxel
induced peripheral neuropathy and quality of life. Methods: Research Design: A
quasi-experimental research design was used to conduct the study. Subjects: A
purposive sample of 60 adult subjects newly diagnosed with breast cancer and treated
with paclitaxel. Setting: This study was conduct at oncology treatment center and
nuclear medicine department at Qena university hospital. Data collection Tools: Four
tools were used for data collection: Tool I: Breast cancer patient’s structured
interview questionnaire. Tool II: The Chemotherapy Induced Peripheral Neuropathy
Assessment (CIPNA). Tool III: Functional Breast (FACT-Tool IV. Neuropathy
Grading Assessment Scale. Results: The mean Assessment of Cancer Therapy
scores of PIPN -QOL for the study group increased one and two months after bundle
of care implementation compared to upon admission in the study with highly
statistically significant differences between them at p < 0.001. Statistically significant
differences regarding sensory and motor neuropathy grading (G1, G2, G3, and G4)
was found after one and after two months of implementing bundle of care instructions
between both group p≤ 0.05. Conclusion: Implementing bundle of care has a positive
effect on PIPN-QOL. The study group demonstrates a statistically significant
Vol. 33. No.2 May, 2024
287
Tanta Scientific Nursing Journal
(Print ISSN 2314 – 5595 ) ( Online ISSN 2735 – 5519)
improvement regarding sensory/motor neuropathy grading and quality of life.
Recommendations: The bundle of care instructions should serve as the basis for
routine nursing care for patients receiving paclitaxel to improve their peripheral
neuropathy and quality of life.
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